Diagnosis and treatment matthew samuel gambino academy home. Conjunctival lymphoma is a form of cancer but it is usually quite low grade and patients tend to do well with a slow course. Conjunctival lymphoma is the second most common ocular adnexal tumor and generally manifests as a salmonpink patch on the fornix of the eye. A conjunctival cyst is a cyst on your conjunctiva, which is a clear membrane covering your outer eye. Another presentation is that of a chronic follicular conjunctivitis fig. Conjunctival lymphoma classically presents as a chronic, sessile, pinkcolored subepithelial conjunctival mass described as a salmon patch fig. Conjunctival lymphoma is an ocular surface tumor that usually appears as a painless, salmonpink, fleshy patch. Conjunctival lymphoma is most common in the 5th to 7th decades, with a slight female predominance 1,3. Marginal zone bcell lymphoma malttype lymphoma is the most frequent subtype identified on biopsy and immunohistochemical studies. Classification, diagnosis, and management of conjunctival. Approximately 515% of all extranodal lymphomas are found in the ocular adnexal region, with approximately 25%. Diagnosis and management of malignant tumors of the eye. This cyst often looks like a clear bubble on the surface of the eye.
Lymphoma is a cancer of the cells that fight infection b and tcells and can occur anywhere in the body. Pathology analysis of biopsied tissue allows your eye cancer specialist to determine. Lymphoma is a malignant lymphoproliferative tumor that can involve the conjunctiva. Features such as rapid growth, invasion of surrounding tissues, ulceration and presence of feeder vessels support a diagnosis of lymphoma. He reported mild itching and intermittent foreign body sensation. Ocular adnexal lymphomas account for 12% of all nonhodgkins lymphomas. Conjunctival lymphoma can appear clinically identical to reactive lymphoid hyperplasia. Feeder vessels and rapid growth are not typically seen in lymphoma. Slit lamp photo showing salmon colored patch with telangiectatic vessels in caruncle of left eye.
Conjunctival lymphoma classically presents as a chronic, sessile, pinkcolored subepithelial conjunctival mass described as a salmon patch. Conjunctival malt lymphoma characteristically manifests as a painless fleshycoloured salmonpatch lesion arising from the fornix. This smooth, multilobulated mass can resemble follicular or papillary conjunctivitis. Most oals are of the nonhodgkins stage ie extranodal lowgrade bcell variety. Red colored tumors on the eye can be a presenting sign of systemic. It is the third most common malignancy involving the conjunctiva, behind squamous cell carcinoma and melanoma 4. An unusual presentation of pediatric conjunctival mucosa. Conjunctiva is the primary site of involvement in onethird of. More specific key signs for a conjunctival lymphoma include the presence of a fleshy, vascularized, salmoncoloredfishflesh swollen patch that is freely mobile. Physical examination examination can reveal a salmon colored mass or patch, chemosis, ptosis, hyperemia, dryness, and epiphora, among. The differential diagnosis of conjunctival lymphoma includes benign reactive lymphoid hyperplasia, benign ocular surface tumors such as pyogenic granuloma, papilloma, malignant tumors such as squamous cell carcinoma, foreign body granuloma, amyloid deposition, and chronic follicular conjunctivitis. Conjunctival lymphoma classically manifests as a pink salmoncolored, smoothsurfaced subconjunctival mass, sometimes with feeder vessels figure 2. Eye examination revealed a salmoncolored raised lesion involving supranasal bulbar conjunctiva extending to superior fornix of the left eye.